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:: Volume 26, Issue 4 (Iranian Journal of Ophthalmology 2014) ::
2014, 26(4): 217-222 Back to browse issues page
Comparison of Intravenous Lidocaine versus Hyoscine on Prevention of Oculocardiac Reflex in Strabismus Surgery
Mehryar Taghavi Gilani Dr., Mohammad Sharifi Dr. *, Mohammadghasem Etemadi Mashhadi Dr.
, sharifim@mums.ac.ir
Abstract:   (10678 Views)

Purpose: Oculocardiac reflex (OCR) is a frequent event during strabismus surgery. The aim of this study is to compare the preventive effect of intravenous lidocaine and hyoscine on OCR.

Methods: This prospective, randomized clinical trial was performed on 75 patients (5-63 years old) underwent strabismus surgery. Patients divided randomly into three groups. Intravenous hyoscine (0.2 mg/kg), lidocaine (1.5 mg/kg) and distilled water were injected before induction with propofol for each group respectively under standard monitoring. Heart rate, blood pressure and/or cardiac dysrrythmia were recorded immediately before/after injection and muscle hooking. Decrease of heart rate more than 20%, hypotension (decrease more than 20% in systolic or diastolic pressure) or any cardiac dysrrythmia were defined as OCR.

 Results: One hundred and thirty-six muscles were hooked during strabismus surgery. OCR was observed in 44 hooked muscles (32.3%). Reflex was observed in hyoscine (34.2%), lidocaine (24.9%) and control (40.9%) groups (p=0.12). The most stretched muscles which caused OCR were medial rectus (56.8%) and lateral rectus (36.3%) muscles. OCR was greater in patients with age between 5-10 years (56%). 

Conclusion: Intravenous lidocaine and N-buthylbromide hyoscine both could reduce OCR occurrence but the difference was not statistically significant compared to the control group. OCR was seen greater in young patients (5-10 years old). Some patients (specially children) need intervention to restore normal condition.



 Iranian Journal of Ophthalmology 201426(4):217-22 © 2014 by the Iranian Society of Ophthalmology
Keywords: Hyoscine, Lidocaine, Oculocardiac Reflex, Strabismus
Full-Text [PDF 297 kb]   (2671 Downloads)    
Type of Study: Original | Subject: Strabismus
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Taghavi Gilani M, Sharifi M, Etemadi Mashhadi M. Comparison of Intravenous Lidocaine versus Hyoscine on Prevention of Oculocardiac Reflex in Strabismus Surgery. Iranian Journal of Ophthalmology. 2014; 26 (4) :217-222
URL: http://irjo.org/article-1-1029-en.html

Volume 26, Issue 4 (Iranian Journal of Ophthalmology 2014) Back to browse issues page
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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