[Home ] [Archive]   [ فارسی ]  
:: Volume 20, Issue 3 (Iranian Journal of Ophthalmology 2008) ::
2008, 20(3): 19-23 Back to browse issues page
Plaque Radiotherapy in Recurrent or Incomplete-Excised Conjunctival Squamous Cell Carcinoma and Melanoma
Masood Naseripour *, Mohsen Bahmani-Kashkouli, Ramin Jaberi, Gholam-Hossein Aghaee, Ali Ahadian
, masoodnp@yahoo.com
Abstract:   (12755 Views)

Purpose : To assess the results of brachytherapy in patients with recurrent or incomplete excised conjunctival squamous cell carcinoma (SCC) and malignant melanoma.

Methods : Three patients underwent brachytherapy of one eye and one patient underwent brachytherapy of both eyes with ruthenium-106 (RU-106) plaques, all of them had a history of incomplete resection or recurrence of the tumor after surgery. All patients were male with an average age at diagnosis of 54 years (range, 34-76 years).The shape and the size of plaques were determined based on location and size of the suspected area. The plaque was inserted to deliver a target dose of 80-100 Gy in the region of conjunctival malignancy. The diagnosis was squamous cell carcinoma in three eyes and conjunctival melanoma in two eyes. All patients had surgical history of one to three previous excisions with or without cryotherapy before brachytherapy. There were microscopic residual tumors after excision in 2 eyes and recurrent lesion was evident in 3 other eyes. A mean dose of 95 Gy was delivered to the tumor bed.

Results : Complete tumor regression without any evidence of recurrent lesion was obtained in all five eyes. The patients were followed for 32 months on average (range, 18-42 months). No radiation related complication was detected, with an exception of a dry eye in the last follow up.

Conclusion : Brachytherapy with RU-106 plaque is an alternative method for treatment of selected patients with recurrent or residual conjunctival SCC and melanoma.

  

Iranian Journal of Ophthalmology 200820(3):19-23
Keywords: Brachytherapy, Ruthenium-106 Plaque, Conjunctival Squamous Cell Carcinoma, Conjunctival Melanoma
Full-Text [PDF 102 kb]   (3097 Downloads)    
Type of Study: Original | Subject: General
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Naseripour M, Bahmani-Kashkouli M, Jaberi R, Aghaee G, Ahadian A. Plaque Radiotherapy in Recurrent or Incomplete-Excised Conjunctival Squamous Cell Carcinoma and Melanoma. Iranian Journal of Ophthalmology. 2008; 20 (3) :19-23
URL: http://irjo.org/article-1-177-en.html


Volume 20, Issue 3 (Iranian Journal of Ophthalmology 2008) Back to browse issues page
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 4006