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:: Volume 20, Issue 3 (Iranian Journal of Ophthalmology 2008) ::
2008, 20(3): 49-52 Back to browse issues page
Topiramate Induced Bilateral Angle-closure Glaucoma
Rana Sorkhabi Dr. *, Nazli Taheri Dr.
, sorkhabi-r@yahoo.com
Abstract:   (14720 Views)

Purpose : To describe a case of acute angle-closure glaucoma associated with oral topiramate (Topamax, Aria Daroo) therapy

Case report: Two weeks after initiation of oral topiramate therapy for epilepsy, a 35-year-old woman presented with blurred vision and headache. Intraocular pressure in both eyes was significantly elevated and her visual acuity was 20/30 Ocular Uterque (OU). Bilateral conjunctival chemosis, shallow anterior chamber and mild corneal edema were observed. Topiramate therapy was discontinued. Topical therapy was initiated in both eyes with betamethasone, atropine and timolol

Results : Symptoms and signs including vision accuracy, refraction and intraocular pressure resolved over the next 2 weeks.

Conclusion : Topiramate therapy may be associated with ciliochoroidal effusion resulting in angle-closure glaucoma therefore, patients on such therapy should be carefully monitored.


Iranian Journal of Ophthalmology 2008 20(3):49-52
Keywords: Topiramate, Angle-closure Glaucoma, Ciliochoroidal Effusion
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Type of Study: Case report | Subject: General
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Sorkhabi R, Taheri N. Topiramate Induced Bilateral Angle-closure Glaucoma. Iranian Journal of Ophthalmology. 2008; 20 (3) :49-52
URL: http://irjo.org/article-1-183-en.html

Volume 20, Issue 3 (Iranian Journal of Ophthalmology 2008) Back to browse issues page
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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