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:: Volume 23, Issue 4 (Iranian Journal of Ophthalmology 2011) ::
2011, 23(4): 3-12 Back to browse issues page
Comparison of the Success Rate of Trabeculectomy with OculusGen versus Trabeculectomy with Mitomycin C
Naveed Nilforushan Dr. * , Maryam Yadegari Dr., Parsa Hodjat Dr.
, naveednil@yahoo.com
Abstract:   (9993 Views)

Purpose : To compare the effectiveness and safety of trabeculectomy with mitomycin C (MMC) versus trabeculectomy with OculusGen

Methods : In this prospective study 14 eyes of 7 patients with a diagnosis of primary open angle glaucoma (POAG) that required trabeculectomy for both eyes were enrolled. For each patient we randomly performed trabeculectomy with MMC for one eye and trabeculectomy with subconjunctival OculusGen for fellow eye. Main outcome measures were: intraocular pressure (IOP), number of IOP reducing medications and surgical complications. Data analysis was performed using SPSS software version 15.

Results : Mean age of the patients was 59±12.6 years. Mean duration of follow-up was 13±3.7 months for OculusGen group and 14.42±6.6 months for MMC group. Mean preoperative IOP was 19.14±3.8 mmHg with 3.14±0.37 number of medication and at last visit was 14.43±3.3 mmHg with 0.86±1.21 number of medication for OculusGen group. Mean preoperative IOP was 21.71±4.1 mmHg with 2.86±0.89 number of medication and at last visit was 12.29±3.5 mmHg with no medication for MMC group. The cumulative success at last visit was 100% in MMC group and 71.5% in OculusGen group (P=0.008%). No systemic or ocular complications related to MMC or OculusGen were seen.

Conclusion : Trabeculectomy with OculusGen is a safe procedure with IOP reduction, at least in short-term, comparable to trabeculectomy with MMC, but with significantly more requirements for IOP lowering medications.

   

Iranian Journal of Ophthalmology 201123(4):3-12 © 2011 by the Iranian Society of Ophthalmology

Keywords: Glaucoma, Trabeculectomy, OculusGen, Mitomycin C
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Type of Study: Original | Subject: General
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Nilforushan N, Yadegari M, Hodjat P. Comparison of the Success Rate of Trabeculectomy with OculusGen versus Trabeculectomy with Mitomycin C. Iranian Journal of Ophthalmology. 2011; 23 (4) :3-12
URL: http://irjo.org/article-1-541-en.html


Volume 23, Issue 4 (Iranian Journal of Ophthalmology 2011) Back to browse issues page
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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