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:: Volume 24, Issue 4 (Iranian Journal of Ophthalmology 2012) ::
2012, 24(4): 11-18 Back to browse issues page
Mustard Gas-Induced Ocular Injuries: A Review of Manifestations and Managements
Seyed Mansour Razavi Dr., Peyman Salamati Dr. *, Sepehr Feizi Dr., Mohammad Ali Javadi Dr.
, psalamati@tums.ac.ir
Abstract:   (11040 Views)

Purpose : To review ocular surface abnormalities caused by exposure to mustard gas and current approaches to manage its delayed-onset complications

Methods : A total of 198 medical articles related to mustard gas were reviewed using known international medical databases, 114 articles were more relevant to the main aim were selected.

Results : Mustard gas-related ocular injuries can be divided into immediate and late phases. Acute manifestations of varying degrees include eyelid erythema and edema, chemosis, subconjunctival hemorrhage, and epithelial edema, punctate erosions, and corneal epithelial defects. Late complications can cause progressive and permanent reduction in visual acuity (VA) and even blindness and occur in approximately 0.5% of those initially severely wounded. These complications consist of chronic blepharitis, decreased tear meniscus, conjunctival vessel tortuosity, limbal stem cell deficiency, corneal scarring and thinning, and lipid/amyloid deposits. Management of the late complications varies from symptomatic treatment to surgical interventions for dry eye, corneal epithelial instability, limbal stem cell deficiency, and corneal opacity.

Conclusion : Mustard gas-related ocular complications are progressive and some sort of surgical interventions may be ultimately required. A long-term and meticulous follow-up for these patients is warranted.


Iranian Journal of Ophthalmology 201224(4):11-18 © 2012 by the Iranian Society of Ophthalmology
Keywords: Eye Injuries, Chemical Warfare, Mustard Gas
Full-Text [PDF 158 kb]   (2564 Downloads)    
Type of Study: Original | Subject: Anterior segment
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Razavi S M, Salamati P, Feizi S, Javadi M A. Mustard Gas-Induced Ocular Injuries: A Review of Manifestations and Managements. Iranian Journal of Ophthalmology. 2012; 24 (4) :11-18
URL: http://irjo.org/article-1-737-en.html

Volume 24, Issue 4 (Iranian Journal of Ophthalmology 2012) Back to browse issues page
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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