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:: جلد 19، شماره 4 - ( مجله چشم پزشکي ايران 1385 ) ::
جلد 19 شماره 4 صفحات 28-33 برگشت به فهرست نسخه ها
EMLA® Cream Application without Occlusive Dressing before Upper Facial Botulinum Toxin Injection A Randomized, Double-Blind, Placebo-Controlled Trial
دكتر محسن بهمنی کشکولی*، دكتر شبنم سلیمی، دكتر پژمان بختیاری، دكتر مصطفی سلطان سنجری
، bahmanik@yahoo.com
چکیده:   (14611 مشاهده)

Purpose: To assess the effect of EMLA® cream application without occlusive dressing on pain on needling (PN) and pain on injection (PI) felt during multiple botulinum toxin type A (BTA) injections for correction of hyperkinetic upper facial lines

Methods: A Prospective, randomized, double-blind, placebo-controlled clinical trial was conducted on 44 subjects seeking upper facial wrinkles correction. Either EMLA® or placebo cream without occlusive dressing was applied on each side of the upper face at least for 60 minutes prior to injections of BTA. PN and PI scores were measured with Visual Analog Scale (VAS).

Results: Patients age ranged from 27 to 57 (mean=40.95) years. Mean PN score (3.46) was less than PI score (3.61) (non significant) the two scores were highly correlated (r: 0.63, P=0.000). While both PN and PI scores were less in the EMLA® (3.02 and 3.34, respectively) than those of placebo group (3.90 and 3.89, respectively), the difference was statistically significant only for PN score (P=0.000 for PN and P=0.06 for PI). Male subjects had less PN and PI scores than females which was not statistically significant (P=0.66 for PN and 0.63 for PI). Time intervals between the cream application and BTA injections (60 to 110 minutes mean=73.02, SD=10.15) did not have significant effect on the pain scores.

Conclusion: EMLA® cream application without occlusive dressing significantly reduces PN associated with multiple BTA injections. Reduction of PI was not significant. Longer duration of EMLA® cream application (up to 110 minutes) did not show lower pain score in either type of the pain.

 

Iranian Journal of Ophthalmology 200719(4):28-33

واژه‌های کلیدی: EMLA cream، botulinum toxin، facial lines، pain، pain control
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نوع مطالعه: پژوهشی | موضوع مقاله: عمومى
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Bahmani-Kashkouli M, Salimi S, Bakhtiari P, Soltan-Sanjari M. EMLA® Cream Application without Occlusive Dressing before Upper Facial Botulinum Toxin Injection A Randomized, Double-Blind, Placebo-Controlled Trial. Iranian Journal of Ophthalmology. 2007; 19 (4) :28-33
URL: http://irjo.org/article-1-135-fa.html

بهمنی کشکولی محسن، سلیمی شبنم، بختیاری پژمان، سلطان سنجری مصطفی. EMLA® Cream Application without Occlusive Dressing before Upper Facial Botulinum Toxin Injection A Randomized, Double-Blind, Placebo-Controlled Trial. مجله چشم پزشکی ایران. 1385; 19 (4) :28-33

URL: http://irjo.org/article-1-135-fa.html



جلد 19، شماره 4 - ( مجله چشم پزشکي ايران 1385 ) برگشت به فهرست نسخه ها
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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