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:: جلد 19، شماره 4 - ( مجله چشم پزشکي ايران 1385 ) ::
جلد 19 شماره 4 صفحات 43-47 برگشت به فهرست نسخه ها
Adenocarcinoma of Retinal Pigment Epithelium Clinically Diagnosed as Malignant Melanoma A Case Report with Unsystematic Review of Literature
دكتر فهیمه اسدی آملی، دكتر هدیه مرادی، دكتر محمدطاهر رجبی*، دكتر محمد ریاضی اصفهانی
، mt_rajabi@yahoo.com
چکیده:   (24494 مشاهده)

Purpose: True neoplasm (adenocarcinoma) of retinal pigment epithelium (RPE) is very rare since it can be misdiagnosed as intraocular malignant melanoma it is of importance to know the clinical and pathologic aspects of this neoplasm. Here, we report a case of adenocarcinoma of RPE.

Methods: Case report.

Results: A 60-year-old man with progressive loss of the vision of the right eye was enucleated with a clinical diagnosis of malignant melanoma. Grossly, a solid well-circumscribed mass occupying the posterior section of the globe near the optic disc was observed. In histological evaluation, the tumor was composed of cells having large, pleomorphic, and hyperchromatic nuclei and prominent nucleoli with occasional pigmentation. Tumor cells were mostly arranged in a papillary pattern. To differentiate it from melanoma, immunohistochemistry was performed. Epithelial membrane antigen (EMA) was strongly positive and HMB45 was negative this is consistent with the diagnosis of adenocarcinoma of RPE. On systemic evaluation no metastases was found.

Conclusion: Adenocarcinoma of RPE is very rare but it should be considered in the differential diagnosis of malignant melanoma of the eye.

 

Iranian Journal of Ophthalmology 200719(4):43-47
واژه‌های کلیدی: retinal pigment epithelium، malignant melanoma، adenocarcinoma
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نوع مطالعه: پژوهشی | موضوع مقاله: عمومى
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Asadi-Amoli F, Moradi H, Rajabi M, Riazi-Esfahani M. Adenocarcinoma of Retinal Pigment Epithelium Clinically Diagnosed as Malignant Melanoma A Case Report with Unsystematic Review of Literature. Iranian Journal of Ophthalmology. 2007; 19 (4) :43-47
URL: http://irjo.org/article-1-138-fa.html

اسدی آملی فهیمه، مرادی هدیه، رجبی محمدطاهر، ریاضی اصفهانی محمد. Adenocarcinoma of Retinal Pigment Epithelium Clinically Diagnosed as Malignant Melanoma A Case Report with Unsystematic Review of Literature. مجله چشم پزشکی ایران. 1385; 19 (4) :43-47

URL: http://irjo.org/article-1-138-fa.html



جلد 19، شماره 4 - ( مجله چشم پزشکي ايران 1385 ) برگشت به فهرست نسخه ها
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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