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:: جلد 19، شماره 3 - ( مجله چشم پزشکي ايران 1385 ) ::
جلد 19 شماره 3 صفحات 34-37 برگشت به فهرست نسخه ها
Botulinum Toxin, Cranial Nerve, Palsy, Paresis, Sixth Nerve
دكتر محمدرضا طالب نژاد*، دكتر معصومه اقتداری
، talebmor@sums.ac.ir
چکیده:   (18573 مشاهده)

Purpose: To evaluate the effect of botulinum toxin-A as an alternate to surgery in acute complete sixth nerve palsy and to shorten the recovery period.

Methods: Thirty patients with acute complete sixth nerve palsy received 1-10 units of botulinum toxin-A (Dysport) injection in the medial rectus muscle within one month from the onset of palsy. Toxin was injected directly into the muscle belly under local (25 cases) or general (5 cases) anesthesia. At the 1st, 7th, 30th, 90th, and 180th day followup, binocular field of vision, abduction and any residual deviation were measured.

Results: Patients aged between 9mo to 70yrs. 24 (80%) patients had significant improvement in abduction after 3 months and 6 (20%) had <10° abduction. Among treatment failures, 2 were traumatic and 2 were tumoral. Binocular diplopia free field was >75° in 22 (73%). 22 (73%) had no residual esotropia and other 8 patients (27%) had 10-50° residual esotropia which required surgery. No cases of exotropia or globe perforation were encountered.

Conclusion: Injection of botulinum toxin-A is a simple and safe way of treating acute complete sixth nerve palsy eliminating the need for invasive surgical manipulation in majority of cases. It can eliminate diplopia during acute stage of palsy in the cases of spontaneous recovery.

 

Iranian Journal of Ophthalmology 200619(3):34-37
واژه‌های کلیدی: Botulinum Toxin، Cranial Nerve، Palsy، Paresis، Sixth Nerve
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نوع مطالعه: پژوهشی | موضوع مقاله: عمومى
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TalebNejad M, Eghtedari M. Botulinum Toxin-A Injection in Acute Sixth Nerve Palsy. Iranian Journal of Ophthalmology. 2007; 19 (3) :34-37
URL: http://irjo.org/article-1-147-fa.html

طالب نژاد محمدرضا، اقتداری معصومه. Botulinum Toxin, Cranial Nerve, Palsy, Paresis, Sixth Nerve. مجله چشم پزشکی ایران. 1385; 19 (3) :34-37

URL: http://irjo.org/article-1-147-fa.html



جلد 19، شماره 3 - ( مجله چشم پزشکي ايران 1385 ) برگشت به فهرست نسخه ها
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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