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:: جلد 25، شماره 2 - ( مجله چشم پزشکي ايران 1392 ) ::
جلد 25 شماره 2 صفحات 115-122 برگشت به فهرست نسخه ها
Comparison of Retinal Nerve Fiber Layer Profile in Subjects with Myopia and Emmetropia Using Scanning Laser Polarimetry
دکتر رضا زارعی*، دکتر رامین دانشور، دکتر محمد سلیمانی، دکتر محمد رزاقی، دکتر حیدر امینی، دکتر مسعود محمدی، دکتر ساسان مقیمی، دکتر یدا. . اسلامی، دکتر قاسم فخرایی، دکتر سیدعلی طباطبایی
، rzareia@yahoo.com
چکیده:   (12569 مشاهده)

Purpose : To compare retinal nerve fiber layer (RNFL) profile in subjects with myopia and emmetropia using GDx variable corneal compensator (VCC)

Methods : Besides ophthalmologic standard examination (refraction, visual acuity and slit-lamp examination, applanation tonometry, and funduscopy), perimetry and scanning laser polarimetry (SLP) were performed. 171 healthy age-matched subjects with low to high myopia (90 subjects) and emmetropia (81 subjects) underwent RNFL analysis by means of GDx VCC. The mean value of each parameter was compared in myopic and emmetropic eyes.

Results : Mean myopia was 3.43±1.19 diopter (D) (range, -0.50 to -6.50). Except for ratio parameters, RNFL parameters were significantly lower in myopic patients. TSNIT standard deviation (p=0.026), nerve fiber indicator (NFI) (p=0.027), superior/nasal (p<0.0001), max modulation (p=0.003), ellipse modulation (p=0.0244) and Symmetry (p=0.028) were higher in myopic group. In both groups, all of RNFL measurements were within the normal range. There was a gradual decrease in RNFL thickness associated with aging in myopic patients (simple regression analysis, p<0.05). There was also a gradual decrease in temporal-superior-nasal-inferior thickness (TSNIT) average and superior maximum with increasing degree of myopia (simple regression analysis, p<0.05).

Conclusion : RNFL thicknesses gradually decreased with increasing age in myopic patients. Patients with myopia had significantly lower RNFL thickness than normal subjects and, although weakened by wide age range of myopic group, there was a linear negative correlation between severity of myopia and RNFL thickness in myopic patients.

  

Iranian Journal of Ophthalmology 201325(2):115-122 © 2013 by the Iranian Society of Ophthalmology

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نوع مطالعه: پژوهشی | موضوع مقاله: ویتره و رتین
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Zarei R, Daneshvar R, Soleimani M, Razzaghi M, Amini H, Mohammadi M, et al . Comparison of Retinal Nerve Fiber Layer Profile in Subjects with Myopia and Emmetropia Using Scanning Laser Polarimetry. Iranian Journal of Ophthalmology. 2013; 25 (2) :115-122
URL: http://irjo.org/article-1-813-fa.html

زارعی رضا، دانشور رامین، سلیمانی محمد، رزاقی محمد، امینی حیدر، محمدی مسعود، و همکاران. و همکاران.. Comparison of Retinal Nerve Fiber Layer Profile in Subjects with Myopia and Emmetropia Using Scanning Laser Polarimetry. مجله چشم پزشکی ایران. 1392; 25 (2) :115-122

URL: http://irjo.org/article-1-813-fa.html



جلد 25، شماره 2 - ( مجله چشم پزشکي ايران 1392 ) برگشت به فهرست نسخه ها
مجله چشم پزشکی ایران Iranian Journal of Ophthalmology
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