Purpose: To determine the
incidence and risk factors associated with glaucoma following congenital
cataract surgery (CCS) in children under age of 15
Methods: This prospective
cohort (since 2006) consisted of children less than 15 years of age who
underwent cataract surgery with or without intraocular lens (IOL) implantation.
The role of the following factors on the development of glaucoma after CCS
including age at surgery, gender, laterality of the cataract, IOL implantation,
congenital ocular anomalies, intra- and postoperative complications, length of
follow-up, central corneal thickness (CCT) as well as the effect of the age of
onset, time to development of glaucoma, and response to treatment were
Results: Overall, 161 eyes of
96 patients were included in this study of which 28 eyes developed glaucoma.
Incidence of glaucoma was 17.4%. Mean±SD age at surgery was 9.3±6.9 (range,
1-24) months in glaucomatous and 40.4±41.1 (range, 1 m-13.6 year) months in
non-glaucomatous group (p<0.001). All glaucoma patients had the operation
under two years of age. In group 1, 9 (60%) and in group 2, 24 (30%) patients
were female (p=0.001). In group 1, 17 eyes (60.7%) and in the group 2, 41 eyes
(30.8%) were aphakic (p=0.001). Mean time to diagnosis of glaucoma was 111.2
days (range 30-1200 days). Mean follow-up time was 3.1 years (range, 1-6
years). In 22 (78.6%) eyes glaucoma was diagnosed within six months after
surgery. Glaucoma was controlled with medications in 23 eyes (82%) and with
surgery in five eyes.
Conclusion: In this study the
incidence of glaucoma after CCS was 17.4% over a follow-up period of six years.
Younger age at the time of lensectomy increases the risk of secondary glaucoma.
IOL implantation may protect against glaucoma. Female gender was affected more
Iranian Journal of Ophthalmology 201426(1):11-16 © 2014 by the Iranian Society of Ophthalmology